The angel of stasis, or at least the concept of it, sounds cool to me. The player would be very weak compared to other modes, which would necessitate lots of running away. At the same time, with no experience to gain, running away makes great sense. It might be a good idea to let the player start with a nuke, as cybie would be extremely difficult to kill on this mode even with a bfg and lots of cells.
Uniques would be fun in this mode as they would would rarely be incompatible with your "build" (stuff like the minigun would be problematic I guess)