Throwing a bunch of relics out here.
Trumpet of Jericho
Symbol: ?
Destroys all walls of the room you're in. On Maze levels it destroys all walls contiguous with a tile within 3 of you, out to a 21x21 square. On a Cavern level it destroys all walls within some radius of you. Cannot be used when tired, makes you tired.
Skullstaff
Symbol: ?
A staff with a skull on it. Using it tires you out, gibs all corpses you can see, and adds five to the Berserk counter for each corpse. Cannot be used when tired.
Massacre Staff
Symbol: ?
Tires you out and does 20 damage to everything on the level. Including you. Cannot be used when tired. Works like a "The Smell of a Massacre" lever except for the part where it affects you.
Decanter of Endless Water
Symbol: ?
Cannot be used when tired, tires you out, works like a "humid" lever in that every walkable tile of the level except open doors is turned to a water tile.
Wand of Digging
Symbol: ?
Turns the level walls brittle. Makes you tired, can't be used when tired.
Crystal Ball
Symbol: ?
Sets your energy to zero and makes you tired, can't be used when tired. Effectiveness depends on traits and how much you've used it before on this level.
First Use: Gain Intuition 1 until end of level (skip if you already have it)
Second Use: Gain benefits of a computer map (or one level of map with the map system I've seen proposed)
Third Use: Gain benefits of a tracking map
Each time it's used, reveals all enemies' present position and type at time of use (enemies move off as soon as you hit enter to get out of it after first and second use, after third you track them).