hmm...what type of build would you use for AoI? Your standard weapons build (chaingun, anyone?) or one that captilizes on the health restrictions (Iro + Badass)?
EDIT: For anyone who wants to see how badly i play and even worse on AoI because i like my med-packs thankyouverymuch, there's a vid in the Chaosforge Dosrecorder Vids section.
I managed to beat it a couple weeks ago with this build:
EE->EE->Int->Int->Int->SoB->SoB->SoB->EE->
Basically I used the extra ammo space you get for firing wildly into the murk, although that became unneccessary once I got Int 3, then I just focused on raising my damage with my chaingun/plasma rifle and killing things before they got within sight range of me. For the Cyberdemon, I was lucky enough to find a thermonuke, but Int 3 would probably be fine for hitting it from a distance with rockets or BFG shots.