Yeah okay, this thing is pretty awesome - it's like my tactical shotgun, except a bit weaker but with twice the ammo capacity.
oh and it doesn't eat my ammo supply and has the same damage falloff - while having the spread of a normal shotgun. Wunderbar.
God damn! This thing absolutely DESTROYED The Containment Area! "Oh no, archviles! Oh no, corpse destruction! Oh no, they're all dead!"
I don't dispute that it's an awesome weapon. My issue is the fact that the nano pack doesn't make it much more awesome - it still does pretty much everything you described there, and cells are plentiful in the second half of the game.
In contrast, a suit of power armour gives you [5] protection, halves the damage from fire *before* that 5 protection (so that 20 damage from an archvile turns into 5 damage), provides 25% melee protection, and regenerates it's durability so that you need never go without ridiculously good armour.
For my money, nano packs should be used by whizkids on nanomachic non-shotgun weaponry (rocket launchers and plasmaguns, mainly), antigrav boots, or powered armour. Nanofibre skin armour can also be ridiculous on certain exotics (especially energy-shielded vest).
For non-whizkids, it's power armour almost every time, and when it's not (ie I already have more armour than I'll ever need), it's usually a BFG or a rocket launcher, not a shotgun.