I've always had better luck with Blademaster or Malicious Blades than with Vampyre. MVm is a COOL trait, I'm not going to deny that, but my personal style is better served by the other two options.
Blademaster is good because you can rapidly close in with a foe and tear them up. Tankiness isn't a huge deal since a berserk status makes any doomguy very hard to kill, and the free action after a kill is a massive plus for Blademaster. Pain Elementals (and their progeny) become trivial, and even packs of 1- to 2-swing enemies die rapidly. Plus, nobody ever said you had to use that free action offensively.
Malicious Blades isn't really a melee-first build, but it plays really well with the item- and upgrade-happy nature of the Technician class. To truly shine, MMB needs Juggler, which can be snagged the very next level after getting the master. Your playstyle changes once you have Juggler- essentially, you trade in the convenience of your prepared slot for a huge defensive buff. Typically, I play a MMB character as a gunfighter first, with a strong melee backup for enemies in my face or melee-weak monsters. Also, rocketjumping is a neat trick that a MMB character can do with almost no pain. It's a great way to conserve actions from a powerup, lets you rapidly close in on an enemy, and is incredibly handy in the Mortuary (since the splash from your rockets will gib corpses!).