Quoting: EvilP
First time I actually tried one was when losing against the cyberdaemon who unfortunately killed me before it went off.
The bomb still goes off after you are dead, so it should still kill him, at least that is what happens for me. Last time this happened I was dead with 7 turns of the bomb to go, and I nuked the sob.
It has also been mentioned that there are at least two other ways to use the bomb...
Quoting: Kornel Kisielewicz
Well, there are at least TWO other uses for it ;-).