My dream rogue is a randomized urban survival against zombies with multiple STARTING points. The zombie fighting angle is obvious, but the starting point thing goes like this:
Depending on what type of character you choose (with the attendant bonuses and penalties) your mission will vary. For example, if you are an unarmed civilian, perhaps either holing up in a house and surviving the night, or making your way to a shelter would be the goal. However, if you are, say, a police officer, or a national militia type, then your increased firepower would be matched with a more difficult objective, like clearing the area around a shelter, or escorting civilians to safe zones. A middle ground would be perhaps a street hoodlum, with better weaponry and combat skills, but no initial shelter, say trying to rescue his family or girlfriend.
Within their limitations, these goals, and the associated maps, could be randomized.
The Key is that the intro map, the triggered quests, and the overall experience would be dependent on what role you choose. The would multiply the replayability.